Actions of depolarizing drugs on paralytic muscle.

Depolarizing Actions of Hydrogen Sulfide on Hypothalamic Paraventricular Nucleus Neurons

Hydrogen sulfide (H2S) is a novel neurotransmitter that has been shown to influence cardiovascular functions as well and corticotrophin hormone (CRH) secretion. Since the paraventricular nucleus of the hypothalamus (PVN) is a central relay center for autonomic and endocrine functions, we sought to investigate the effects of H2S on the neuronal population of the PVN. Whole cell current clamp rec...

Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.

GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4 mM), or pyruvate (5 mM) shifted GABA actions to hyperpolarizing, suggesting that the depolarizing effect...

Actions of antiulcer drugs.

Drugs on Skeletal Muscle

4.5. Bisbenzyl-isoquinolinium compounds 4.5.2. Mivacurium 4.6. Reversal of non-depolarizing neuromuscular block by anticholinesterases 4.7. Other neuromuscular uses of anticholinesterases 4.8. Pharmacokinetics of non-depolarizing neuromuscular blocking drugs 4.8.1 Clearance of non-depolarizing neuromuscular blocking drugs and duration of action 5. Depolarizing neuromuscular blocking drugs 5.1. ...

Programmable Muscle Stimulator for Activating Paralytic Patients

Defective muscles and associated nerves affect the functioning of the parts of the human body leading to paralysis. In order to provide temporal recovery from paralysis the affected muscles can be identified and stimulated in a periodic sequence by driving required electrical current intensity into the muscle. The amplitude, frequency and pulse width of the muscle current are adjusted to see th...